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Circulation / Heart

Effect of Baechu Kimchi Added Ecklonia cava Extracts on High Glucose-induced Oxidative Stress in Human Umbilical Vein Endothelial Cells.
Lee HA, Song YO, Jang MS, Han JS.
Prev Nutr Food Sci. 2014, 19(3), 170-177.

Cardioprotective effects of Eckonia cava polyphenol against doxorubicin-induced cardiotoxicity in an amimal rat model with the evidence of electron microscopic finding.
Ahn, HS, Jeon, HK, Kim GH, Chung, WB, Cho, JS, Kim MJ, Cho, EJ, Jung, HO, Youn, HJ.
J Am Coll Cardiol. 2014, 63(12_S), A873.

Alga Ecklonia bicyclis, Tribulus terrestris, and glucosamine oligosaccharide improve erectile function, sexual quality of life, and ejaculation function in patients with moderate mild-moderate erectile dysfunction: a prospective, randomized, placebo-controlled, single-blinded study.
Sansalone S, Leonardi R, Antonini G, Vitarelli A, Vespasiani G, Basic D, Morgia G, Cimino S, Russo GI.
Biomed Res Int. 2014, 2014, 121396.

Cardioprotective effects of seapolynol (polyphenol purified from ecklonia cava) against adriamycin-induced cardiomyopathy in an animal rat model.
Jeon HK, Lee DH, Youn HJ, Shin HC.
European J Heart Failure. 2013, 12(1), S101.

Observational study: daily treatment with a new compound ""tradamixina"" plus serenoa repens for two months improved the lower urinary tract symptoms.
Iacono F, Prezioso D, Illiano E, Ruffo A, Romeo G, Amato B.
BMC Surg. 2012, 12 (Suppl 1), S22.

Sexual asthenia: Tradamixina versus Tadalafil 5 mg daily.
Iacono F, Prezioso D, Illiano E, Romeo G, Ruffo A, Amato B.
BMC Surg. 2012, 12 (Suppl 1), S23.

Insulinotrophic and hypolipidemic effects of Ecklonia cava in streptozotocin-induced diabetic mice.
Kim MJ, Kim HK.
Asian Pac J Trop Med. 2012, 5(5), 374-379.

Antithrombotic and profibrinolytic activities of eckol and dieckol.
Kim TH, Ku SK, Bae JS.
J Cell Biochem. 2012, 113(9), 2877-2883.

Vascular barrier protective effects of phlorotannins on HMGB1-mediated proinflammatory responses in vitro and in vivo.
Kim TH, Ku SK, Lee T, Bae JS.
Food Chem Toxicol. 2012, 50(6), 2188-2195.

Pancreatic Lipase Inhibitory Activity of Phlorotannins Isolated from Eisenia bicyclis.
Eom SH, Lee MS, Lee EW, Kim YM, Kim TH.
Phytother Res. 2012, 27, 148-151.

Effects of 12-week Oral Supplementation of Ecklonia cava Polyphenols on Anthropometric and Blood Lipid Parameters in Overweight Korean Individuals: A Double-blind Randomized Clinical Trial.
Shin HC, Kim SH, Park Y, Lee BH, Hwang HJ.
Phytother Res. 2012, 26(3), 363-368.

Effects of Ecklonia cava Polyphenol in Individuals with Hypercholesterolemia: A Pilot Study.
Lee DH, Park MY, Shim BJ, Youn HJ, Hwang HJ, Shin HC, Jeon HK.
J Med Food. 2012, 15(11), 1038-1044.

Cardioprotective effects of seapolynol (polyphenol purified from ecklonia cava) against adriamycin-induced cardiomyopathy in an animal rat model.
Jeon HK, Lee DH, Shin HC, Youn HJ, Kim KT.
European Heart J. 2012, 33(Supl 1), 328.

Effect of phlorotannins isolated from Ecklonia cava on angiotensin I-converting enzyme (ACE) inhibitory activity.
Wijesinghe WA, Ko SC, Jeon YJ.
Nutr Res Pract. 2011, 5(2), 93-100.

Protective effects of dieckol isolated from Ecklonia cava against high glucose-induced oxidative stress in human umbilical vein endothelial cells.
Lee SH, Han JS, Heo SJ, Hwang JY, Jeon YJ.
Toxicol In Vitro. 2010, 24(2), 375-381.

Protective effects of enzymatic digest from Ecklonia cava against high glucose-induced oxidative stress in human umbilical vein endothelial cells.
Lee SH, Heo SJ, Hwang JY, Han JS, Jeon YJ.
J Sci Food Agric. 2010, 90(2), 349-356.

Ecklonia cava extracts inhibit lipopolysaccharide induced inflammatory responses in human endothelial cells
Kim TH, Bae JS.
Food Chem Toxicol. 2010, 48(6), 1682-1687.

Anti-hyperlipidemic dffect of an edible brown algae, Ecklonia stolonifera, and its constituents on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats.
Yoon NY, Kim HR, Chung HY, Choi JS.
Arch Pharm Res. 2008, 31(12), 1564-1571.

An anticoagulative polysaccharide from an enzymatic hydrolysate of Ecklonia cava.
Athukorala Y, Jung WK, Vasanthan T, Jeon YJ,
Carbohydrate Polymers. 2006, 66(2), 184-191.

Antihypertensive effect of Ecklonia cava extract.
Hong JH, Son BS, Kim BK, Chee HY, Song KS, LeeBH, Shin HC, Lee KB.
Kor J Pharmacogn. 2006, 37(3), 200-205.

Angiotensin-converting enzyme I inhibitory activity of phlorotannins from Ecklonia stolonifera.
Jung HA, Hyun SK, Kim HR, Choi JS.
Fisheries Sci. 2006, 72(6), 1292–1299.

Angiotensin I-converting enzyme inhibitory activities of beverages made from sea algae and commercially available tea extracts .
Nagai T, Suzuki N, Nagashima T.
J Food Agri Environ. 2006, 4(3-4), 17-19.

Antioxidative properties of brown algae polyphenolics and their perspectives as chemopreventive agents against vascular risk factors.
Kang K, Park YJ, Hwang HJ, Kim SH, Lee JG, Shin HC.
Arch Pharm Res. 2003, 26(4), 286-293.

Anti-plasmin inhibitor. VI. Structure of phlorofucofuroeckol A, a novel phlorotannin with both dibenzo-1,4-dioxin and dibenzofuran elements, from Ecklonia kurome OKAMURA.
Fukuyama Y, Kodama M, Miura I, Kinzyo Z, Mori H, Nakayama Y, Takahashi M.
Chem Pharm Bull (Tokyo). 1990, 38(1), 133-135.

Anti-plasmin inhibitor. V. Structures of novel dimeric eckols isolated from the brown alga Ecklonia kurome OKAMURA.
Fukuyama Y, Kodama M, Miura I, Kinzyo Z, Mori H, Nakayama Y, Takahashi M.
Chem Pharm Bull (Tokyo). 1989, 37(9), 2438-2440.

An anti-plasmin inhibitor, Eckol, isolated from the brown algae Ecklonia kurome OKAMURA.
Nakayama Y, Takahashi M, Fukuyama Y. Kinzyo Z.
Agric Biol Chem. 1989, 53(11), 3025-3030.

Structure of an anti-plasmin inhibitor, Eckol, isolated from the brown alga Ecklonia kurome
OKAMURA and inhibitory activities of Its derivatives on plasma plasmin inhibitors. Fukuyama Y, Kodama M, Miura I, Kinzyo Z, Kido, M, Mori H, Nakayama Y, Takahashi M.
Chem Pharm Bull (Tokyo). 1989, 37(2), 349-353.

Eckols, Novel Phlorotannins with a Dibenzo-p-Dioxin Skeleton Possessing Inhibitory Effects on a2-Mcroblobulin from the Brown Alga Ecklonia kurome Okamura.
Fukuyama Y, Miura I, Kinzyo Z, Mori H, Kido M, Nakayama Y, Takahashi M, Ochi M,
Chem. Lett. 1985, 739-742.