Microbiology

Seanol Science Center Presentation
2020, June 14.

Antiviral Activities of Sea Polyphenol. Seanol Science Center

Seanol Science Center Presentation
2020, June 18.

Antibacterial Activities of Sea Polyphenol. Seanol Science Center

Bioorg Med Chem. 2013, 21(13), 3730-3737.

Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava.
Park JY, Kim JH, Kwon JM, Kwon HJ, Jeong HJ, Kim YM, Kim D, Lee WS, Ryu YB.

J Agric Food Chem. 2011, 59(12), 6467-6473.

Influenza Virus Neuraminidase Inhibitory Activity of Phlorotannins from the Edible Brown Alga Ecklonia cava.
Ryu YB, Jeong HJ, Yoon SY, Park JY, Kim Y, Park SJ, Rho MC, Kim SJ, Lee WS.

Mar Drugs. 2019, 17(3), 149.

Dereplication by High-Performance Liquid Chromatography (HPLC) with Quadrupole-Time-of-Flight Mass Spectroscopy (qTOF-MS) and Antiviral Activities of Phlorotannins from Ecklonia cava.
Cho HM, Doan TP, Ha TKQ, Kim HW, Lee BW, Pham HTT, Cho TO, Oh WK.

Mar Drugs. 2019, 17(5), 299.

Different Antifungal Activity of Anabaena sp., Ecklonia sp., and Jania sp. against Botrytis cinerea.
Righini H, Baraldi E, García Fernández Y, Martel Quintana A, Roberti R.

Indian J Microbiol. 2018, 58(1), 105-108.

In Vitro Antibacterial Activity of Phlorotannins from Edible Brown Algae, Eisenia bicyclis Against Streptomycin-Resistant Listeria monocytogenes.
Kim HJ, Dasagrandhi C, Kim SH, Kim BG, Eom SH, Kim YM.

Viruses. 2018, 10(9), 465.

Virucidal and Synergistic Activity of Polyphenol-Rich Extracts of Seaweeds against Measles Virus.
Morán-Santibañez K, Peña-Hernández MA, Cruz-Suárez LE, Ricque-Marie D, Skouta R, Vasquez AH, Rodríguez-Padilla C, Trejo-Avila LM.

Fish Shellfish Immunol. 2018, 72, 273-281.

Efficacy of algal Ecklonia cava extract against viral hemorrhagic septicemia virus (VHSV).
Yang HK, Jung MH, Avunje S, Nikapitiya C, Kang SY, Ryu YB, Lee WS, Jung SJ.

Int J Syst Evol Microbiol. 2017, 67(8), 3089-3094.

Flavivirga eckloniae sp. nov. and Flavivirga aquimarina sp. nov., isolated from seaweed Ecklonia cava.
Lee JH, Kang JW, Choe HN, Seong CN.

Biomed. Mater. 2016, 11(4), 045015.

Enrichment of enzymatically mineralized gellan gum hydrogels with phlorotannin-rich Ecklonia cava extract Seanol® to endow antibacterial properties and promote mineralization.
Douglas TE, Dokupil A, Reczyńska K, Brackman G, Krok-Borkowicz M, Keppler JK, Božič M, Van Der Voort P, Pietryga K, Samal SK, Balcaen L, van den Bulcke J, Van Acker J, Vanhaecke F, Schwarz K, Coenye T, Pamuła E.

Fish Shellfish Immunol. 2016, 54, 620-628.

A prebiotic role of Ecklonia cava improves the mortality of Edwardsiellatarda-infected zebrafish models via regulating the growth of lactic acid bacteria and pathogen bacteria.
Lee W, Oh JY, Kim EA, Kang N, Kim KN, Ahn G, Jeon YJ.

Fish Shellfish Immunol. 2016, 51, 313-320.

A prebiotic effect of Ecklonia cava on the growth and mortality of olive flounder infected with pathogenic bacteria.
Lee W, Ahn G, Oh JY, Kim SM, Kang N, Kim EA, Kim KN, Jeong JB, Jeon YJ.

J Microbiol Biotechnol. 2014, 24(4), 465-474.

Inhibitory effects of brown algae extracts on histamine production in mackerel muscle via inhibition of growth and histidine decarboxylase activity of Morganella morganii.
Kim DH, Kim KB, Cho JY, Ahn DH.

Biosci Biotechnol Biochem. 2014, 78(7), 1151-1158.

Anti-HIV-1 activity of phlorotannin derivative 8,4‴-dieckol from Korean brown alga Ecklonia cava.
Karadeniz F, Kang KH, Park JW, Park SJ, Kim SK.

Appl Microbiol Biotechnol. 2014, 98(23), 9795-9804.

The mechanism of antibacterial activity of phlorofucofuroeckol-A against methicillin-resistant Staphylococcus aureus.
Eom SH, Lee DS, Jung YJ, Park JH, Choi JI, Yim MJ, Jeon JM, Kim HW, Son KT, Je JY, Lee MS, Kim YM.

Appl Biochem Biotechnol. 2013, 171(3), 569-582.

Application of yeast Candida utilis to ferment Eisenia bicyclis for enhanced antibacterial effect.
Eom SH, Lee DS, Kang YM, Son KT, Jeon YJ, Kim YM.

PLoS One. 2013, 8(8), e72203.

Antifungal activity of phlorotannins against dermatophytes and yeasts: approaches to the mechanism of action and influence on Candida albicans virulence factor.
Lopes G, Pinto E, Andrade PB, Valentão P.

Bioorg Med Chem. 2013, 21(15), 4706-4713.

In vitro antiviral activity of phlorotannins isolated from Ecklonia cava against porcine epidemic diarrhea coronavirus infection and hemagglutination.
Kwon HJ, Ryu YB, Kim YM, Song N, Kim CY, Rho MC, Jeong JH, Cho KO, Lee WS, Park SJ.

Phytother Res. 2013, 27(8), 1260-1264.

In Vitro Antibacterial Activity and Synergistic Antibiotic Effects of Phlorotannins Isolated from Eisenia bicyclis Against Methicillin-Resistant Staphylococcus aureus.
Eom SH, Kim DH, Lee SH, Yoon NY, Kim JH, Kim TH, Chung YH, Kim SB, Kim YM, Kim HW, Lee MS, Kim YM.

PLoS One. 2012, 7(2), e31145.

Can phlorotannins purified extracts constitute a novel pharmacological alternative for microbial infections with associated inflammatory conditions?
Lopes G, Sousa C, Silva LR, Pinto E, Andrade PB, Bernardo J, Mouga T, Valentão P.

Food Chem Toxicol. 2012, 50(9), 3251-3255.

Antimicrobial effect of phlorotannins from marine brown algae.
Eom SH, Kim YM, Kim SK.

J Korean Soc Appl Biol Chem. 2010, 53(4), 504-507.

Antifungal Activities of Dieckol Isolated from the Marine Brown Alga Ecklonia cava against Trichophyton rubrum.
Lee MH, Lee KB, Oh SM, Lee BH, Chee HY.

Foodborne Pathog Dis. 2010, 7(4), 435-441.

Antibacterial Activity of Ecklonia cava Against Methicillin-Resistant Staphylococcus aureus and Salmonella spp.
Choi JG, Kang OH, Brice OO, Lee YS, Chae HS, Oh YC, Sohn DH, Park H, Choi HG, Kim SG, Shin DW, Kwon DY.

Biotechnol Bioproc E 13, 758–764 (2008).

Synergistic effect between dieckol from Ecklonia stolonifera and β-lactams against methicillin-resistant Staphylococcus aureus.
Lee D, KangM, Hwang H, Eom S, Yang J, Lee M, Lee W, Jeon Y, Choi J, Kim Y.

Bioorg Med Chem. 2008, 16(17), 7921-7926.

Anti-HIV-1 activity of phloroglucinol derivative 6,6'-bieckol from Ecklonia cava.
Artan M, Karadeniz F, Lee SH, Kim MM, Kim SK.

Biol Pharm Bull. 2004, 27(4), 544-547.

Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava.
Ahn MJ, Yoon KD, Min SY, Lee JS, Kim JH, Kim TG, Kim SH, Kim NG, Huh H, Kim J.

Aquaculture. 2003, 218(1-4), 601-611.

Algicidal effect of phlorotannins from the brown alga Ecklonia kurome on red tide microalgae.
Nagayama K, Shibata T, Fujimoto K, Honjo T, Nakamura T.

J Antimicrob Chemother. 2002, 50(6), 889-893.

Bactericidal activity of phlorotannins from the brown alga Ecklonia kurome.
Nagayama K, Iwamura Y, Shibata T, Hirayama I, Nakamura T.

Planta Med. 1985, 51(4), 308-312.

Antibiotics from Algae. XXXV. Phlorotannins from Ecklonia maxima.
Glombitza KW, Vogels HP.

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